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pede4d The goal of this study was to determine whether a phosphodiesterase-4D (PDE4D) allosteric inhibitor (BPN14770) would improve cognitive function and behavioral outes in patients with fragile X. The goal of this study was to determine whether a phosphodiesterase-4D (PDE4D) allosteric inhibitor (BPN14770) would improve cognitive function and behavioral outcomes in patients

pede4d, The N-terminus conserved domain UCR1 and UCR2 mentioned above play an important role in dimerization of PDE4D and in the regulation of the catalytic domain [13],.